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Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

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Innovation In Blood Establishment Processes, Strasbourg, 2025: A Conference Report.

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Innovation In Blood Establishment Processes, Strasbourg, 2025: A Conference Report.

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Innovation in Blood Establishment Processes, Strasbourg, 2025: a Conference Report.

Marie Pflieger¹, Annika Sepich¹, Julie Harriague²

¹European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe, Strasbourg, France.

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|November 3, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

The European Directorate for the Quality of Medicines & Healthcare conference focused on innovations in blood establishment processes. Discussions centered on the new Substances of Human Origin (SoHO) Regulation for enhanced safety and supply continuity.

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Area of Science:

Transfusion Medicine
Regulatory Science
Public Health

Background:

The European Union (EU) is transitioning from existing directives to the new Substances of Human Origin (SoHO) Regulation (EU) 2024/1938, effective in 2027.
This regulatory shift aims to harmonize approaches across the EU for substances derived from human sources.
Ensuring high quality and safety standards for SoHO is critical for donor and recipient protection and supply chain integrity.

Purpose of the Study:

To summarize key discussions and innovations presented at the international EDQM Blood Conference.
To explore the implications of the upcoming SoHO Regulation on blood establishment processes.
To foster awareness regarding the benefits and challenges associated with implementing the new SoHO Regulation.

Main Methods:

The report is based on the proceedings and discussions from the international EDQM Blood Conference on Innovation in Blood Establishment Processes.
Key topics and expert insights shared during the conference sessions were documented.
The focus was on identifying innovative practices and regulatory advancements in the blood sector.

Main Results:

The conference highlighted the significant impact of the forthcoming SoHO Regulation on harmonizing quality and safety standards for blood and blood components.
Participants shared diverse experiences and innovative strategies in blood donation and processing.
The discussions underscored the need for preparedness to address both the advantages and hurdles in adopting the new regulatory framework.

Conclusions:

The implementation of the SoHO Regulation is expected to enhance health protection and ensure a stable supply of critical SoHO.
Collaboration and knowledge sharing are vital for successfully navigating the transition to the new regulatory landscape.
Continued innovation in blood establishment processes is essential to meet evolving healthcare needs and regulatory requirements.