Harris Hawks optimization based deep learning models for heart disease diagnosis

Isabella S1, Lokeshraja B1, Nithish Narayan M1

  • 1School of Computing, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India.

Scientific Reports
|November 3, 2025
PubMed

Insights

This study introduces a deep learning model for early heart disease prediction, utilizing K-mode clustering and Harris Hawks Optimization (HHO) for feature selection. The Gated Recurrent Unit (GRU) model achieved 88.03% accuracy, offering efficient diagnostic solutions.

Area of Science:

  • Cardiology
  • Artificial Intelligence
  • Data Science

Background:

  • Heart disease is a major global health issue, necessitating accurate early diagnostic tools.
  • Predictive modeling using deep learning offers a promising avenue for improving cardiovascular disease detection.

Purpose of the Study:

  • To develop and validate a deep learning-based predictive system for early heart disease diagnosis.
  • To enhance model efficiency and accuracy through optimized data preparation and feature selection.

Main Methods:

  • Utilized the Cardiovascular Disease dataset (70,000 records).
  • Employed K-mode clustering for data optimization and Harris Hawks Optimization (HHO) for feature selection.
  • Implemented and evaluated various deep learning architectures, including Gated Recurrent Unit (GRU).

Main Results:

  • The GRU model achieved the highest prediction accuracy at 88.03%.
  • HHO-based feature selection improved model efficiency by removing redundant features.
  • Performance was evaluated using precision, recall, accuracy, and AUC score via ROC curve analysis.

Conclusions:

  • Deep learning methodologies, combined with advanced feature selection techniques like HHO, are highly effective for early cardiovascular disease detection.
  • The developed system provides an efficient diagnostic solution scalable for various health applications.