A Case of Synchronous Bilateral Spermatocytic Tumor

Area of Science:

• Oncology
• Uropathology

Background:

• Spermatocytic tumor is a rare testicular neoplasm, distinct from classical seminoma.
• It typically presents as a unilateral, slow-growing mass in older men, accounting for ~1% of testicular tumors.

Purpose of the Study:

• To report a rare case of synchronous bilateral spermatocytic tumor.
• To emphasize the diagnostic challenges and importance of immunohistochemistry in such cases.

Main Methods:

• Case presentation of a 54-year-old man with bilateral testicular masses.
• Histopathological examination and immunohistochemistry (SALL4, PLAP, c-kit, Vimentin) were performed.

Main Results:

• Diagnosis of bilateral spermatocytic tumors confirmed via immunohistochemistry.
• Patient developed hypogonadism post-surgery, managed with testosterone replacement.
• No recurrence observed at 1-year follow-up.

Conclusions:

• Synchronous bilateral spermatocytic tumors are rare and should be considered in older men with bilateral testicular masses.
• Immunohistochemistry is crucial for accurate diagnosis, distinguishing it from seminoma.