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Penile Metastasis From Castration-Resistant Prostate Cancer: A Case Report
Satoshi Asakura1, Yoshihiro Nakagami1, Tatsuki Inoue1
1Department of Urology Showa Medical University School of Medicine Tokyo Japan.
IJU Case Reports
|August 10, 2026
Summary
Penile metastasis, a rare complication of advanced prostate cancer, presents a poor prognosis. This case highlights the importance of recognizing this unusual presentation for timely palliative care.
Area of Science:
- Urology
- Oncology
Background:
- Penile metastasis from prostate cancer is a rare clinical finding.
- It is generally associated with advanced stages of the disease and a poor prognosis.
Purpose of the Study:
- To report a case of penile metastasis from prostate cancer.
- To emphasize the importance of awareness for early recognition and management.
Main Methods:
- A case presentation of a 65-year-old male with metastatic hormone-sensitive prostate cancer.
- Review of treatment progression including androgen receptor signal inhibitor therapy and chemotherapy.
- Biopsy confirmation of penile metastasis.
Main Results:
- The patient presented with advanced prostate cancer and widespread metastases.
- Developed penile metastasis during disease progression despite multiple treatment modalities.
- The patient had a poor outcome, dying 5 months after diagnosis of penile metastasis.
Conclusions:
- Penile metastasis from prostate cancer is rare and signifies advanced disease.
- Increased awareness can aid in early diagnosis, palliative care, and patient counseling.
