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Diana Lucas1, André Gomes1, Josué Pereira2,3

  • 1Neurosurgery, Centro Hospitalar Universitário de São João, Porto, PRT.

Cureus
|November 4, 2025
PubMed

Keywords:
cervical sarcomaintracranial ascending metastizationpediatric hydrocephalussubcutaneus tissue pathventriculoperitoneal shunt

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Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...