Related Experiment Video
Updated: Jan 12, 2026
Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
Published on: October 24, 2025
Reproductive Donors' Needs and Preferences: A Mixed-methods Systematic Review
Elnaz Iranifard1,2, Robab Latifnejad Roudsari3,4, Malihe Amirian5
1Department of Midwifery, May.C., Islamic Azad University, Maybod, Iran.
Background:
Reproductive donation is a challenging task, in which donors' needs are sometimes neglected. To provide reproductive donors with well-structured, evidence-based, and donor-centered care, it is essential to acknowledge their unique needs and preferences. This study aimed to synthesize the current evidence regarding donors' needs and preferences.
Methods:
This mixed-methods systematic review (MMSR) was conducted based on the recommended approach for MMSR by the Joanna Briggs Institute (JBI) manual for data synthesis. The databases of Web of Science, PubMed, Cochrane Library, and Scopus were searched by two researchers separately, using keywords such as "egg donor", "sperm donor", "ovum donor", "gamete donor", "embryo donor", desire, expectation, preference, and need without a time limit, up to December 2024. Original research articles regarding reproductive donors' needs, written in English, were included in the study. Reviews, commentaries, letters to the editor, book chapters, and theses were excluded. Quality assessment was carried out by two researchers using JBI tools for cross-sectional, cohort, and qualitative studies. Data were synthesized by the convergent integrated approach by three researchers.
Results:
Through data synthesis of 34 eligible articles, six categories of reproductive donors' needs and preferences emerged. These categories included 1) Need for support, 2) Informational needs, 3) Need for counseling, 4) Requirement for financial policies, 5) Preference towards recognition of donors' rights, and 6) Need for preserving donors' dignity and respect.
Conclusion:
Various reproductive donors' needs and preferences are not completely met by the current care provided by fertility clinics. Healthcare policymakers and fertility clinics must consider the donors' needs and preferences in policymaking and/or clinical practice to provide the services that donors deserve.Registration: The protocol of this systematic review has been registered in PROSPERO (CRD42024588821).
