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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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One-year mortality in patients undergoing aortic valve replacement and its relationship with the extent of myocardial

Luis A Vega-Quesada1, Néstor A Parra-Ordoñez1, Heber J Pech-Ortega2

  • 1Department of Cardiology, High Specialty Medical Unit, Hospital de Cardiología #34 Dr. Alfonso J. Treviño Treviño, Centro Médico Nacional del Noreste, Monterrey, N.L., Mexico.

Archivos De Cardiologia De Mexico
|November 4, 2025
PubMed

Insights

One-year mortality after aortic valve replacement was 6%. Myocardial damage staging did not correlate with mortality, but a high Society of Thoracic Surgeons (STS) score and low left ventricular ejection fraction (LVEF) were significant risk factors.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Clinical Outcomes Research

Background:

  • Aortic valve replacement (AVR) is a critical procedure for severe aortic valve disease.
  • Understanding predictors of mortality post-AVR is essential for patient management.
  • The role of myocardial damage extension in predicting outcomes after AVR requires further investigation.

Purpose of the Study:

  • To determine the 1-year mortality rate in patients who underwent aortic valve replacement.
  • To assess the relationship between myocardial damage extension and 1-year mortality.
  • To identify clinical risk factors associated with mortality post-AVR.

Main Methods:

  • An observational, retrospective, cross-sectional, and comparative study.
  • Inclusion of 177 patients aged over 18 who underwent AVR between March 2019 and March 2021.
  • Classification of patients into myocardial damage stages (0-4) to analyze 12-month mortality and associated risk factors.

Main Results:

  • The overall 1-year mortality rate was 6% (11/177).
  • Mortality was predominantly observed in myocardial damage stages 2 and 3.
  • Hypertension and diabetes mellitus were the most frequent comorbidities among deceased patients.
  • A left ventricular ejection fraction (LVEF) < 30% and a Society of Thoracic Surgeons (STS) score > 2% were identified as risk factors for mortality.

Conclusions:

  • The myocardial damage extension staging did not significantly correlate with 1-year mortality after AVR.
  • An STS score greater than 2% and an LVEF less than 30% are significant risk factors for mortality post-AVR.
  • These findings highlight the importance of pre-operative risk assessment using established scores and cardiac function parameters.
Abstract

Keywords:
Aortic stenosisExtent of myocardial damageMortality

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