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Radiostereometric analysis for evaluating inducible fracture micromotion: a scoping review.
Michaela Manalili Hansen1, Mohammad Laith Ballo2, Stephan Maximillian Röhrl2
1Department of Orthopaedic Surgery, Odense University Hospital, Odense; Institute of Clinical Medicine, University of Southern Denmark, Odense, Denmark. michaela.manalili.hansen@rsyd.dk.
Acta Orthopaedica
|November 5, 2025
Summary
Radiostereometric analysis (RSA) can measure inducible fracture micromotion, offering a direct assessment of healing. This review of 7 studies highlights varied methods but shows RSA
Area of Science:
- Orthopedics
- Biomedical Engineering
- Radiology
Background:
- Fracture healing assessment relies on indirect methods like radiographs.
- Inducible fracture micromotion offers a direct measure of healing.
- Radiostereometric analysis (RSA) precisely measures micromotion but has limited clinical use.
Purpose of the Study:
- To map literature on RSA for inducible fracture micromotion.
- To summarize methodological approaches for future research.
- To guide standardized RSA application in fracture healing assessment.
Main Methods:
- Systematic literature search of Medline, Embase, and Scopus.
- Inclusion of clinical studies using RSA for inducible fracture micromotion.
- Data extraction on study design, patient population, fracture type, loading, and outcomes.
Main Results:
- Seven clinical studies were reviewed, with small sample sizes (6-16 patients).
- Fractures included distal radius, femur, proximal tibia, and pelvis.
- RSA detected inducible motion and distinguished union from non-union, despite varied protocols.
Conclusions:
- Heterogeneous methods exist for RSA in fracture micromotion assessment.
- Standardized approaches are needed for wider clinical adoption.
- RSA shows promise for objective fracture healing evaluation.
