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Electrostrategies in orthopaedic research.
Jing-Cheng Cao1,2,3, Ze-Yu Shang4, Yi-Fan Zhang1,2,3
1Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Biomaterials Translational
|November 5, 2025
Summary
Electrostrategies using electrical stimulation show growing importance in orthopaedic research. This bibliometric analysis maps key trends, institutions, and future directions for bone healing and tissue engineering.
Area of Science:
- Orthopaedic research
- Biomaterials science
- Biomedical engineering
Background:
- Electrostrategies, including electrical stimulation and conductive/piezoelectric biomaterials, are increasingly vital in orthopaedics.
- A comprehensive bibliometric overview of this field is currently lacking.
Purpose of the Study:
- To conduct a bibliometric analysis of electrostrategies in orthopaedic research.
- To identify trends, key contributors, influential journals, and thematic clusters.
- To highlight future research directions and potential clinical applications.
Main Methods:
- Bibliometric analysis of 2810 publications from 1980 onwards.
- Identification of key institutions, authors, and journals.
- Keyword and co-occurrence analysis to determine prevalent themes and research clusters.
Main Results:
- Two distinct phases of progress identified since 1980, indicating increasing research emphasis.
- North America, Europe, and Asia identified as hubs of activity.
- Prevalent themes include "electrical-stimulation," "bone," and "in vitro," focusing on bone growth, proliferation, differentiation, and surgical applications.
- Key research clusters identified: "electrical-stimulation," "bone," "surgery," and "bone-mineral density."
Conclusions:
- Essential research directions include developing conductive/piezoelectric biomaterials and electrically-guided stem cell differentiation.
- Electrostrategies hold significant potential for improving orthopaedic treatments and patient quality of life.
- Future research should refine electrical stimulation parameters, develop novel piezoelectric materials, and advance personalized tissue engineering.
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