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Updated: Jan 12, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
A patient-centred approach to malignant pleural effusion
Matthew Shorthose1, Rebecca Crook2, Rahul Bhatnagar2
1Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
Malignant pleural effusion (MPE) treatment now emphasizes outpatient symptom control and patient-centered goals. New options like indwelling pleural catheters (IPC) and local anesthetic thoracoscopy (LAT) improve management for complex cases.
Area of Science:
- Pulmonology
- Oncology
- Palliative Care
Background:
- Malignant pleural effusion (MPE) affects up to 20% of cancer patients, often with poor prognosis.
- Historically, pleurodesis was the primary treatment for MPE.
- MPE commonly arises from breast or lung primary cancers.
Purpose of the Study:
- To review current literature on malignant pleural effusion (MPE) treatment.
- To focus on patient-centered care and evolving management strategies for MPE.
- To explore updated treatment options for MPE.
Main Methods:
- Systematic literature review using PubMed.
- Focus on recent publications regarding MPE management.
- Analysis of patient-centered care approaches in MPE treatment.
Main Results:
- Shift towards outpatient management and symptom control for MPE.
- Introduction of new treatments like indwelling pleural catheters (IPC) and local anesthetic thoracoscopy (LAT).
- Management strategies for complex MPE, including non-expansile lungs and septated effusions, utilizing fibrinolytics and IPC.
Conclusions:
- Malignant pleural effusion (MPE) treatment has evolved significantly over 15 years.
- Current MPE management prioritizes outpatient care and symptom control.
- Individualized patient discussions are crucial for effective MPE treatment planning.
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