Related Experiment Video
Updated: Jan 12, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Effectiveness of the navigation of cancer chemoradiotherapy patients: a retrospective cohort study
Marina Araujo da Cruz Moraes1, Michelli Cristina Silva De Assis2, Aline Marques Acosta2
1Hospital de Clínicas de Porto Alegre, Serviço de Enfermagem Onco-hematológica. Porto Alegre, Rio Grande do Sul, Brasil.
Objective:
To verify the effectiveness of a navigation program for cancer patients undergoing concomitant chemoradiotherapy treatment in a public hospital, regarding treatment completion, emergency service visits and unplanned hospitalizations.
Method:
Retrospective double cohort study conducted in a hospital in southern Brazil. Adults with cancer referred for concomitant chemoradiation were included from January 2022 to December 2023. Participants were divided into before and after navigation program groups. Univariate analysis and Poisson regression were performed to assess outcomes.
Results:
A total of 100 patients were evaluated in the before navigation group and 112 in the after navigation group. After the implementation of the program, there was a higher percentage of patients who achieved complete treatment (66% versus 89.3%; p<0.001), a lower percentage of emergency room visits (50% versus 31.3%; p=0.008) and hospital admissions (57% versus 33; p=0.001). In the multivariate analysis adjusted for exposure variables, no significant effect was observed for the primary outcome (p>0.05).
Conclusion:
Improvements in treatment success and a decrease in the use of emergency services and hospitalizations were observed, although more robust evidence is needed to prove the full effectiveness of the navigation program, no significant associations were identified in the multivariate analysis that proves the effectiveness of the navigation program.
Related Concept Videos
Cancer Survival Analysis
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies
There are several types of targeted therapies against...
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

