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A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
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Interlimb training improves motor function in partial-hand but not necessarily transradial simulated prosthesis use.

Bennett L Alterman1, Saif Ali1, Emily Keeton1

  • 1School of Biological Sciences, Georgia Institute of Technology, 555 14th Street, Room 1309E, Atlanta, GA, 30332-0356, USA.

Scientific Reports
|November 5, 2025
PubMed
Summary

Interlimb training may improve motor control for upper limb amputation rehabilitation. Partial-hand prosthesis users showed greater benefits than transradial prosthesis users in this 5-day study.

Keywords:
AdaptationAmputationMotor learningRehabilitationUpper limb

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Area of Science:

  • Rehabilitation Medicine
  • Neuroscience
  • Prosthetics & Bionics

Background:

  • Functional rehabilitation is crucial in acute/subacute stages post-upper limb amputation.
  • Interlimb training offers a potential method for transferring learned skills from the unaffected to the affected limb.
  • This approach is particularly relevant while awaiting prosthesis fitting.

Purpose of the Study:

  • To investigate the efficacy of a 5-day interlimb training paradigm on motor control in individuals using prosthesis simulators.
  • To determine if interlimb training yields greater improvements in partial-hand prosthesis users compared to transradial prosthesis users.
  • To assess the impact of interlimb training on both simple and complex reach-to-grasp tasks.

Main Methods:

  • Participants with intact limbs performed simple and complex reach-to-grasp tasks using body-powered transradial or partial-hand prosthesis simulators.
  • A 5-day interlimb training protocol was implemented.
  • Motor control improvements were assessed pre- and post-training.

Main Results:

  • Partial-hand prosthesis users demonstrated greater performance adaptations with interlimb training compared to transradial prosthesis users.
  • Transradial prosthesis users showed minimal to no improvement following the training.
  • Partial-hand users exhibited significantly higher reach peak velocities post-training in both simple and complex tasks.

Conclusions:

  • Interlimb training shows promise for early-stage rehabilitation following upper limb amputation.
  • The benefits of interlimb training appear more pronounced for individuals with partial-hand loss.
  • Further research can explore optimizing interlimb training protocols for diverse amputation levels.