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Nanofibrillar conductive hydrogel adhesive for soft bioelectronic interfaces.
Yibo Huang1, Shuo Sun1, Chunhui Li1
1School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China. fetwang@scut.edu.cn.
Materials Horizons
|November 6, 2025
Summary
This study presents a new conductive hydrogel adhesive for real-time monitoring of human motion and physiological signals like ECG and EMG. Its advanced design ensures reliable, long-term use in soft bioelectronic interfaces.
Area of Science:
- Biomaterials Science
- Soft Electronics
- Medical Devices
Background:
- Conventional hydrogels lack mechanical resilience, tissue adhesion, and electrical conductivity for soft bioelectronic interfaces.
- Reliable monitoring of physiological signals requires advanced materials that overcome these limitations.
Purpose of the Study:
- To develop a conductive nanofibrillar double-network hydrogel adhesive.
- To enable real-time, long-term monitoring of human motion and physiological signals (ECG, EMG, respiration).
Main Methods:
- Fabrication of a double-network hydrogel matrix.
- Incorporation of silver nanoparticle-doped protein nanofibrils.
- Characterization of mechanical properties, tissue adhesion, and electrical conductivity.
Main Results:
- The hydrogel adhesive demonstrated tunable mechanical properties and strong tissue adhesion.
- Ultra-sensitive strain responsiveness allowed precise detection of various body movements and physiological signals.
- Successful demonstrations in large animal models for lung injury sealing and monitoring.
Conclusions:
- The developed hydrogel adhesive is suitable for reliable, long-term soft bioelectronic interfaces.
- It enables precise monitoring of human motion and physiological signals.
- Potential applications include early detection of abnormalities and personalized healthcare interventions.
