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Updated: Jan 12, 2026
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Isolation of Atrial Cardiomyocytes from a Rat Model of Metabolic Syndrome-related Heart Failure with Preserved Ejection Fraction
Published on: July 26, 2018
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Cardiac amyloidosis
Adam Dhayyat1, Peter S Deeg1, Jacek Srokosz1
1Kardiologisk avdeling, Sykehuset Østfold, Kalnes.
Summary
Cardiac amyloidoma, a rare localized amyloid deposit, can mimic tumors and cause severe heart obstruction. This case emphasizes prompt diagnosis in young adults with unusual cardiac symptoms using transesophageal echocardiography.
Area of Science:
- Cardiology
- Pathology
Background:
- Cardiac amyloidosis involves protein deposits in the heart muscle, often presenting as restrictive cardiomyopathy.
- Amyloidoma is a rare, localized, tumor-like form of cardiac amyloidosis.
Purpose of the Study:
- To report a rare case of cardiac amyloidoma presenting as an intracardiac tumor.
- To highlight the diagnostic challenges and clinical importance of considering cardiac tumors in young adults.
Main Methods:
- Case presentation of a middle-aged man with constitutional symptoms.
- Diagnostic workup included transesophageal echocardiography (TEE).
- Surgical exploration and histopathological examination confirmed amyloidoma.
Main Results:
- The patient presented with lethargy, chest discomfort, and fever.
- TEE revealed intracardiac masses causing severe obstruction and elevated diastolic pressure.
- Histopathology confirmed cardiac amyloidoma, despite a perioperative fatality.
Conclusions:
- Cardiac amyloidoma is an extremely rare entity with potentially fatal hemodynamic compromise.
- Early consideration of cardiac tumors and urgent TEE are crucial for patients with atypical cardiac symptoms.
- This case underscores the importance of timely diagnosis in young adults presenting with unusual cardiac presentations.
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