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Class-incremental learning using push-pull autoencoder for chest X-ray diagnosis.

Jayant Mahawar1, Angshuman Paul1

  • 1Department of Computer Science and Engineering, Indian Institute of Technology Jodhpur, N.H. 62, Nagaur Road, Karwar, Jodhpur, 342030, Rajasthan, India.

Computers in Biology and Medicine
|November 6, 2025
PubMed
Summary
This summary is machine-generated.

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Class-incremental learning (CIL) models for chest X-ray diagnosis were improved using the Push-Pull Autoencoder (PPAE). PPAE reduces catastrophic forgetting, enhancing diagnostic accuracy for new and old diseases.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Machine Learning

Background:

  • Class-incremental learning (CIL) enables models to learn new classes without prior data, crucial for evolving medical datasets.
  • Existing CIL models struggle with chest X-ray diagnosis, while deep learning models for X-rays often exhibit catastrophic forgetting in CIL settings.

Purpose of the Study:

  • To develop a novel CIL framework tailored for chest X-ray analysis, addressing the limitations of current models.
  • To mitigate catastrophic forgetting and improve diagnostic performance in incremental learning scenarios for medical imaging.

Main Methods:

  • Proposed the Push-Pull Autoencoder (PPAE), a model utilizing a dual latent space to disentangle abnormality-specific and abnormality-agnostic features.
  • Implemented a coreset generation algorithm to select representative exemplars, preserving knowledge from previous classes without full retraining.
Keywords:
Chest X-ray diagnosisClass-incremental learningContrastive learningCoresetPush-pull autoencoder

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  • Trained PPAE to refine feature representations by clustering similar samples and distinguishing dissimilar ones based on learned features.
  • Main Results:

    • Achieved up to 3% improvement in F1 score and 4% improvement in AUROC across diverse chest X-ray datasets.
    • Demonstrated significant reduction in catastrophic forgetting, maintaining high diagnostic accuracy on previously learned classes.
    • Validated the framework's robustness and effectiveness in continuous learning tasks for chest X-ray diagnosis.

    Conclusions:

    • The PPAE framework effectively addresses catastrophic forgetting in class-incremental learning for chest X-ray diagnosis.
    • The proposed method enhances continuous learning capabilities, offering a promising approach for evolving medical diagnostic systems.
    • PPAE shows potential for advancing long-term, adaptive diagnostic solutions in medical imaging.