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Updated: Jan 12, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Limiting central venous catheter access for blood sampling and its impact on central line-associated bloodstream
Mary Beth Hovda Davis1, Takaaki Kobayashi2, Kathryn Trautman3
1University of Iowa College of Nursing, Iowa City, IA; University of Iowa Stead Family Children's Hospital, Iowa City, IA.
Background:
Central venous catheters (CVCs) pose a risk of infection through fluid infusion, medication administration, and blood draws. We conducted a scoping review evaluating the risk of accessing a CVC and aiming to identify strategies for limiting CVC usage to decrease the incidence of central line-associated bloodstream infections (CLABSIs) in hospital settings.
Methods:
This review adheres to the methodological framework proposed by Arksey and O'Malley and is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. Searches were conducted in the CINAHL, EMBASE, PubMed, and Scopus databases, focusing on publications from the past decade.
Results:
Six studies met inclusion criteria. Three interventions were identified: (1) establishing standardized CVC sampling times, (2) utilizing phlebotomists to perform peripheral blood cultures, and (3) avoiding the use of CVCs for both blood cultures and routine blood draws.
Conclusions:
Increased frequency of CVC access is associated with a higher risk of CLABSI. Interventions to reduce CVC access for blood draws can effectively lower CLABSI rates. Identifying and implementing strategies such as use of phlebotomy teams and standardized sampling protocols may help guide hospital policies and improve patient safety outcomes. Future research should focus on prospective evaluation of these approaches.
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