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The Effect Of Visual Deprivation During Cognitive Motor Dual Task Training On Cognitive Function In Type 2 Diabetes
J Anandh Raj1, Ramesh Chandra Patra1, Kavitha S2
1Lovely Faculty of Applied Medical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India.
F1000Research
|November 7, 2025
Summary
Cognitive motor dual-task blindfold training (CMDBT) combined with exercise significantly improved cognitive function in type 2 diabetes mellitus (T2DM) patients. This approach offers a promising addition to T2DM rehabilitation programs.
Area of Science:
- Neuroscience
- Exercise Physiology
- Endocrinology
Background:
- Type 2 diabetes mellitus (T2DM) is associated with cognitive decline.
- Cognitive motor dual-task blindfold training (CMDBT) may improve cognition by activating procedural memory.
- The potential benefits of CMDBT combined with exercise for T2DM cognitive function require investigation.
Purpose of the Study:
- To evaluate the effectiveness of CMDBT combined with aerobic and resistance exercises on cognitive function in individuals with T2DM.
- To compare the cognitive benefits of CMDBT plus exercise versus exercise alone in T2DM patients.
Main Methods:
- A single-center, parallel-group randomized controlled trial was conducted.
- Sixty-two adults with T2DM were randomized into an experimental group (CMDBT + exercise) or a control group (exercise only).
- Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) before and after a 12-week intervention.
Main Results:
- The experimental group showed a significant improvement in MoCA scores (mean increase of 3.32 points), exceeding the minimal clinically important difference.
- The control group demonstrated a smaller improvement in MoCA scores (0.94 points).
- The adjusted between-group difference in MoCA scores was significantly greater in the CMDBT group (2.38 points, p=0.0001).
Conclusions:
- CMDBT combined with conventional exercises significantly enhances cognitive function in individuals with T2DM.
- This combined approach is more effective than exercise or CMDBT alone for improving cognition in T2DM.
- CMDBT integration into T2DM rehabilitation programs is supported by these findings.
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