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The first mitochondrial genome of Haemagogus equinus from Jamaica

Simone L Sandiford1,2, Simmoy A A Noble3, Samra A Pierre4

  • 1Department of Basic Medical Sciences, Pharmacology and Pharmacy Section, Faculty of Medical Sciences, The University of the West Indies Mona, Kingston, Jamaica.

F1000Research
|November 7, 2025
PubMed

Insights

This study presents the first mitochondrial genome for the mosquito *Haemagogus equinus*, a potential vector for arboviruses like Mayaro virus (MAYV). This genetic data aids in understanding mosquito taxonomy and arboviral transmission dynamics in the Americas.

Area of Science:

  • Medical Entomology
  • Genomics
  • Arbovirology

Background:

  • Arboviral infections, including Mayaro virus (MAYV), are increasing in the Americas.
  • Mosquitoes in the *Haemagogus* genus are known vectors for arboviruses but are understudied.
  • *Haemagogus equinus* is present in Jamaica and adapted to human-populated areas, yet its role in disease transmission is unclear.

Purpose of the Study:

  • To report the first mitochondrial genome sequence for *Haemagogus equinus*.
  • To provide genetic data for improved taxonomic classification and understanding of arboviral vector potential.
  • To address the lack of genetic information and morphological identification challenges within the *Haemagogus* genus.

Main Methods:

  • Genome skimming approach using Illumina Novaseq 6000.
  • Sequencing of two *Hg. equinus* mosquito specimens.
  • Assembly of the mitochondrial genome using NOVOplasty.

Main Results:

  • A complete mitochondrial genome of 16,471 bp was assembled for *Hg. equinus*.
  • The mitogenome has a high AT content (80.7%) and comprises 37 genes.
  • Phylogenetic analysis confirmed *Hg. equinus*'s placement within the Albomaculatus section of the *Haemagogus* subgenus.

Conclusions:

  • The first mitochondrial genome of *Hg. equinus* provides crucial genetic data for this understudied arboviral vector.
  • Phylogenetic placement supports existing taxonomic classifications of the *Haemagogus* genus.
  • This genomic resource is vital for future research on arboviral transmission and vector control strategies.
Keywords:
Haemagogus equinusJamaicaarbovirusesgenome skimmingmitogenome

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