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Advancements and Clinical Applications of Machine Learning for Hand Pose Estimation.

Lainey G Bukowiec1, Jasmin Valenti2, Linjun Yang3

  • 1Mayo Clinic Orthopedic Surgery Artificial Intelligence Lab, Rochester, MN; Mayo Clinic Department of Orthopedic Surgery, Rochester, MN.

The Journal of Hand Surgery
|November 7, 2025
PubMed
Summary

Hand pose estimation using machine learning shows promise for clinical use. Challenges include computational needs, anatomical complexity, and limited clinical data for training models, especially for hand pathologies.

Keywords:
Artificial intelligencedeep learninghand pose estimationmachine learningvision-based

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Area of Science:

  • Biomedical Engineering
  • Computer Vision
  • Machine Learning

Background:

  • Hand pose estimation is crucial for clinical applications, enabling precise capture of hand kinematics.
  • Current methods include vision-based (e.g., RGB-D cameras) and sensor-based (wearable devices) approaches.
  • Machine learning significantly advances the accuracy of hand pose prediction using complex datasets.

Purpose of the Study:

  • To review the current state of hand pose estimation for clinical applications.
  • To identify key challenges hindering the widespread adoption of these technologies in healthcare.
  • To highlight the need for improved methods and datasets, particularly for pathological conditions.

Main Methods:

  • Review of existing literature on vision-based and sensor-based hand pose estimation techniques.
  • Analysis of machine learning models applied to hand pose estimation.
  • Identification of common challenges and limitations in current research.

Main Results:

  • Hand pose estimation methods have shown significant progress, particularly with machine learning integration.
  • Computational demands and the intricate anatomy of the hand present ongoing technical hurdles.
  • A critical lack of diverse clinical datasets, especially for hand pathologies, impedes robust model training.

Conclusions:

  • Despite advancements, significant challenges persist in computational requirements and anatomical complexity for accurate hand pose estimation.
  • The scarcity of specialized clinical datasets, particularly for conditions affecting the hand, remains a major bottleneck for developing effective machine learning models.
  • Further research is needed to overcome these limitations and fully realize the clinical potential of hand pose estimation.