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Related Concept Videos

Applications Of NMR In Biology01:25

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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
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Nanodiamonds in Advancing Biomedical Sciences.

Ebenezer Owusu1, Sofia Lerma1, Jinhyeong Jang2

  • 1Department of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Brownsville, Texas 78520, United States.

ACS Applied Materials & Interfaces
|November 7, 2025
PubMed
Summary
This summary is machine-generated.

Fluorescent nanodiamonds (FNDs) offer unique properties for advanced biomedical applications. This review explores their potential in diagnostics and therapies, especially for neurological disorders.

Keywords:
bioimagingbiosensingdrug deliveryfluorescent nanodiamondsnanodiamondsneurological disordersquantum biosensingspin-based diagnosticssurface functionalization

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Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Nanotechnology

Background:

  • Nanodiamonds (NDs) possess unique optical, thermal, and mechanical properties, distinct from other carbon nanomaterials.
  • Their high surface-to-volume ratio and versatile surfaces enable applications in catalysis, electronics, and life sciences.
  • NDs' biocompatibility facilitates controlled interactions with biological systems, making them promising for biomedical applications.

Purpose of the Study:

  • To review the fundamental principles of nanodiamonds (NDs) and fluorescent nanodiamonds (FNDs).
  • To highlight emerging biomedical applications of NDs and FNDs, with a focus on neurological disorders.
  • To discuss challenges and translational potential for NDs in neural therapies.

Main Methods:

  • Review of ND and FND properties, synthesis, and surface functionalization.
  • Analysis of current literature on ND and FND applications in bioimaging, biosensing, drug delivery, and quantum technologies.
  • Examination of ND applications in neurological disorder research and potential therapeutic strategies.

Main Results:

  • Fluorescent nanodiamonds (FNDs) show significant potential in spin-enhanced bioimaging, biosensing, and drug delivery.
  • NDs and FNDs offer unique advantages for developing novel biomedical technologies and material biointerfaces.
  • Emerging applications show promise for NDs and FNDs in addressing neurological disorders.

Conclusions:

  • NDs and FNDs are versatile nanomaterials with significant potential in advanced biomedical applications.
  • Further research and development are needed to overcome challenges for clinical translation, particularly in neural therapies.
  • NDs represent a promising multifunctional platform for future therapeutic interventions.