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Updated: Jan 12, 2026

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
Published on: October 11, 2018
Maternal sleep disorders during pregnancy: Potential threats to offspring metabolism and possible interventions
Haiyan Chen1, Yaolin Ren1, Yuan Zeng1
1Key Laboratory of Endocrinology, Ministry of Health, Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China.
Abstract:
The uterine microenvironment exerts a significant and lasting influence on metabolic health later in life. The incidence of sleep disorders during pregnancy is high. Sleep disorders not only increase the risk of maternal complications during pregnancy but also may lead to increased susceptibility to metabolic diseases in offspring during adulthood by influencing the fetal development environment. In this review, we explored the effects of maternal sleep disorders during pregnancy on the metabolic health of offspring, the potential mechanisms, and intervention measures, with the aim of providing more scientific guidance for pregnancy care and promoting the health of mothers and offspring.
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