Related Experiment Video
Updated: Aug 14, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
The effect of phospholipids on anaphylactic histamine release
Abstract:
1. Histamine release by antigen from three sensitized rat tissues is potentiated by phosphatidyl serine (PS). The effect is greatest with isolated peritoneal cells. Phosphatidyl inositol, ethanolamine, choline and phosphatidic acid are inactive.2. PS greatly increases the rate of antigen-induced histamine release and only slightly prolongs the duration of the release process.3. PS shows a concentration-dependent effect over the range 1-10 mug/ml. At 10 mug/ml it is active over a wide range of antigen concentrations.4. Calcium ions are necessary for the potentiation by PS of antigen-induced histamine release from rat peritoneal cells.
More Related Videos
Related Concept Videos
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Allergic Reactions
Allergic Drug Reactions
Drug Toxicity: Allergic Reactions
Allergic Reactions: Anaphylaxis
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

