Related Experiment Video
Updated: Jan 12, 2026
12:59
Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
13.0K
Comparative Effectiveness of Exercise and Protein-Based Interventions on Muscle Strength, Mass, and Function in
Ruixiang Yan1, Shiqi Jia1, Di Lu1
1School of Athletic Training, Guangzhou Sport University, Guangzhou, Guangdong, China.
The Journal of Nutrition, Health & Aging
|November 8, 2025
Summary
Combining resistance and balance training with protein supplementation is the most effective strategy for improving muscle strength, physical function, and mass in individuals with sarcopenia.
Area of Science:
- Gerontology
- Exercise Physiology
- Nutritional Science
Background:
- Sarcopenia management guidelines recommend exercise and protein supplementation.
- This study compared various exercise types and nutritional strategies for sarcopenia outcomes.
Purpose of the Study:
- To compare the effectiveness of different exercise interventions combined with nutritional strategies for sarcopenia.
- To evaluate impacts on muscle strength, physical function, and muscle mass.
Main Methods:
- Systematic literature search of major databases (PubMed, Embase, Web of Science, Cochrane) up to December 2024.
- Frequentist random-effects network meta-analysis with GRADE certainty assessment.
- Interventions categorized by effectiveness and certainty ratings.
Main Results:
- Resistance and balance training plus nutrition (RBT + Nu) most effectively improved grip strength, gait speed, SPPB, and skeletal muscle index.
- RBT alone excelled in the timed up and go test; aerobic, resistance, and balance training with nutrition improved the five-times sit-to-stand test.
- Resistance training with nutrition yielded the greatest gains in knee extension strength and appendicular skeletal muscle mass; combined aerobic, resistance, and balance training maximized balance performance.
Conclusions:
- High-certainty evidence confirms RBT + Nu as the optimal intervention for sarcopenia.
- Combining resistance and balance training with protein and amino acid supplementation is recommended for feasible implementation.
Related Concept Videos
01:27Exercise and Muscle Performance
2.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.3K
02:26Protein Networks
4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
01:21Overview of Protein Metabolism
3.6K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
3.6K