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High Thymidine Kinase 1 Activity Linked to Poor Breast Cancer Survival: A Systematic Review and Meta-Analysis

Simin Li1, Guoxue Tang1, Shuzhen Lin1

  • 1Department of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.

Clinical Breast Cancer
|November 8, 2025
PubMed
Summary

High thymidine kinase 1 activity (TK1a) levels in breast cancer patients indicate a worse prognosis for overall survival (OS) and progression-free survival (PFS). This biomarker may help predict patient outcomes.

Keywords:
BiomarkerClinicopathological parametersEstrogen receptorHazard ratioPrognosis

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