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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

725
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
725
Depression: Overview01:18

Depression: Overview

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Related Experiment Video

Updated: Jan 11, 2026

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
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Exploring the Relationship Between Depression and Attention-Deficit/Hyperactivity Disorder Symptoms in Children Using

Jinuk Kim1, Sang-Woo Hahn2, Wayne Warburton3

  • 1Institute for Basic Science, Sungkyunkwan University, Suwon, Republic of Korea.

Psychiatry Investigation
|November 9, 2025
PubMed
Summary
This summary is machine-generated.

In children with attention-deficit/hyperactivity disorder (ADHD), specific brainwave activities correlate with symptom severity. Delta brainwaves may indicate depression, while alpha and theta waves reflect ADHD symptom intensity.

Keywords:
AdolescentAttention-deficit/hyperactivity disorderChildDepressionElectroencephalography

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Area of Science:

  • Neuroscience
  • Child Psychology
  • Psychiatry

Background:

  • Depression frequently co-occurs with attention-deficit/hyperactivity disorder (ADHD) in children.
  • The neurophysiological basis linking ADHD symptoms and depression requires further investigation.

Purpose of the Study:

  • To explore the neurophysiological underpinnings of depression comorbidity in children with ADHD.
  • To identify potential brainwave markers for ADHD symptom severity and depression.

Main Methods:

  • A cross-sectional study involving 87 children diagnosed with ADHD.
  • Quantitative electroencephalography (qEEG) recordings were analyzed.
  • Correlations between qEEG spectral power and symptom severity (ADHD, depression, anxiety) were examined.

Main Results:

  • Negative correlation between frontal, central, and parietal theta activity and ADHD symptom severity.
  • Positive correlation between alpha activity in the same regions and ADHD symptom severity.
  • Negative correlation between delta activity and depression severity.

Conclusions:

  • Alpha and theta activity may serve as neurophysiological markers for ADHD symptom severity.
  • Delta activity could be a biological marker for depression severity in children with ADHD.
  • Further research is recommended to validate these findings.