Related Experiment Video
Updated: Jan 11, 2026

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
Published on: April 16, 2019
Climatic Factors and Inflammatory Skin Disorders.
Kristen Fernandez1, Alex Ha1, Xiaochen Zhong1
1Dermatology Service, San Francisco VA Health Care System, San Francisco, CA 94121, USA.
Climate change negatively impacts skin health, worsening inflammatory conditions like psoriasis and acne. Rising temperatures, pollution, and extreme weather are key environmental drivers affecting skin disorders.
Area of Science:
- Dermatology and Environmental Health
- Cutaneous Biology
- Climate Change Research
Background:
- Environmental factors, including climate change, are increasingly recognized for their role in skin health.
- Rising global temperatures, air pollution, UV radiation, and extreme weather events pose significant threats to skin integrity.
- These climatic factors can directly and indirectly trigger or exacerbate inflammatory skin conditions.
Purpose of the Study:
- To comprehensively review and summarize existing research on the effects of climatic factors on specific inflammatory skin disorders.
- To assess the impact of environmental changes on common and rare skin conditions.
- To provide a consolidated understanding of climate-driven skin pathology.
Main Methods:
- Systematic literature review of studies investigating climate variables and skin disorders.
- Analysis of research assessing the influence of temperature, air pollution, UV radiation, and extreme weather.
- Focus on inflammatory skin conditions including psoriasis, acne, seborrheic dermatitis, and lupus.
Main Results:
- Climate-driven factors demonstrably exacerbate inflammatory skin disorders.
- Increased temperature, air pollution, and UV radiation are linked to worsening of psoriasis and acne.
- Extreme weather events can precipitate or aggravate conditions such as lupus and seborrheic dermatitis.
Conclusions:
- Climatic changes represent a significant environmental burden on skin health, leading to increased prevalence and severity of inflammatory dermatoses.
- Understanding these climate-skin interactions is crucial for public health strategies and clinical management of skin diseases.
- Further research is warranted to elucidate specific mechanisms and develop targeted interventions against climate-related skin exacerbations.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Response
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...

