Microplastics, Skin Disease, and Dermatology: Evidence and Perspectives

Microplastics and nanoplastics are found ubiquitously in the environment and might pose risks to skin health. Some particles can penetrate the skin, especially if the skin barrier is compromised. In-vitro studies show that micro-plastics and nano-plastics (MNPs) may cause oxidative stress, trigger inflammation, and induce senescence in fibroblasts. Dermatologists should consider the potential impact of MNPs on skin homeostasis and promote adequate use and disposal of plastics in their personal and occupational settings. This article calls for research on the topic and advocates for plastic-free or bio-degradable alternatives that do not exert adverse effects to mitigate potential risks.