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Related Experiment Video

Updated: Jul 24, 2026

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Acupuncture combined with exercise therapy for Sarcopenia in the elderly: A multicenter randomized controlled study

Yangchi Li1,2,3,4, Yu Lu1,2,3,4, Wengxiong Li1,2,3,4

  • 1Shaanxi University of Chinese Medicine, Xianyang 712046, China.

Methodsx
|November 10, 2025
PubMed
Summary

Acupuncture combined with exercise shows promise for treating sarcopenia, an age-related muscle loss condition. This study aims to provide robust evidence for acupuncture as an effective adjuvant therapy for sarcopenia.

Keywords:
AcupunctureIrisinMulti-center studyMyostatinSarcopeniaSham control group

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Area of Science:

  • Gerontology and Rehabilitation Medicine
  • Integrative and Complementary Medicine
  • Clinical Trial Design

Background:

  • Sarcopenia is a progressive age-related loss of muscle strength and mass, significantly impacting older adults' quality of life and safety.
  • The global aging population is driving an increase in sarcopenia incidence, presenting a major public health concern.
  • While preclinical studies suggest acupuncture's efficacy, robust clinical trials for sarcopenia are lacking, particularly those with sham controls and multicenter designs.

Purpose of the Study:

  • To investigate the efficacy of acupuncture as an adjuvant therapy for sarcopenia.
  • To provide robust evidence through a well-designed randomized controlled trial.
  • To establish a comprehensive assessment framework for sarcopenia.

Main Methods:

  • A multicenter randomized controlled trial integrating acupuncture with exercise therapy.
  • Inclusion of a control group receiving sham acupuncture alongside exercise to mitigate placebo effects.
  • Utilization of a comprehensive and validated set of outcome measures for rigorous assessment.

Main Results:

  • This section is to be populated upon study completion.

Conclusions:

  • This study is expected to provide strong evidence for acupuncture's role in managing sarcopenia.
  • Findings will contribute to expanding the conceptual framework for sarcopenia assessment.
  • The research aims to validate acupuncture as a viable adjuvant treatment for sarcopenia.