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Updated: Jan 11, 2026

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
Published on: February 24, 2023
Melioidosis clinically unresponsive to meropenem in a traveller returning from Thailand
Ilka Grewe1,2,3,4, Anette Hennigs1, Flaminia Olearo5
1I Department of Internal Medicine, Division of Infectious Diseases, University Medical Center Hamburg-Eppendorf, Martinistraße 52, Hamburg 20251, Germany.
Abstract:
Burkholderia pseudomallei can cause severe systemic infection with involvement of multiple organs and abscess formation. Carbapenems are considered superior to ceftazidime in severe cases. We here report a case of Melioidosis in a previously healthy 57-year-old traveller. Despite in vitro testing confirming susceptibility of the isolate for meropenem, the patient's clinical condition did not improve during seven days of meropenem treatment. After changing the treatment regimen to high-dose ceftazidime, the patient's clinical condition and laboratory parameters rapidly improved. Thus, we here report a rare case of Melioidosis clinically unresponsive to meropenem.
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