Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

5.3K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.3K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

940
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
940
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

8.8K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
8.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bilateral Cystoid Macular Edema After Light Treatment With Light-Adjustable Lens.

Cureus·2025
Same author

Resolution of Vitreomacular Traction Following a Commercial Flight Simulator Experience.

Journal of vitreoretinal diseases·2025
Same author

Povidone-Iodine as an Adjuvant Therapy for Refractory Gonorrhea Keratoconjunctivitis: A Case Report.

Cureus·2025
Same author

Lipoid proteinosis, a rare cause of eyelid margin lesions.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2025
Same author

Update on Epidemiologic Trends in Causes of Childhood Blindness and Severe Visual Impairment in East Africa.

International ophthalmology clinics·2024
Same author

Childhood vision impairment and blindness in West Africa: public health measures and implications for systemic health.

Frontiers in medicine·2024

Related Experiment Video

Updated: Jan 11, 2026

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

754

Higher Order Aberrations Induced by Light Adjustable Lens Treatment.

Traeson Brandenburg1, Nathaniel Ashby1, Drew Dickson2

  • 1Creighton University School of Medicine, Omaha, Nebraska.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|November 10, 2025
PubMed
Summary

Light Adjustable Lens (LAL) treatments generally do not induce significant higher order aberrations (HOAs). However, patients with prior refractive surgery may experience a greater increase in HOAs after LAL treatment.

More Related Videos

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

548
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.9K

Related Experiment Videos

Last Updated: Jan 11, 2026

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

754
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

548
Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses
06:55

Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

Published on: June 6, 2017

7.9K

Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Cataract surgery and refractive lens exchange are common procedures.
  • Light Adjustable Lens (LAL) technology offers customizable visual correction post-implantation.
  • Understanding induced aberrations is crucial for refractive outcomes.

Purpose of the Study:

  • To quantify higher order aberrations (HOAs) induced by Light Adjustable Lens (LAL) treatments.
  • To assess the clinical significance of these induced HOAs.

Main Methods:

  • Retrospective chart review of patients undergoing LAL implantation.
  • Corneal, internal, and total HOAs measured using iTrace aberrometry.
  • HOAs analyzed before adjustments, at lock-in, and post-treatment.

Main Results:

  • Mean total HOAs induced were minimal (-0.005 μm), with no values exceeding 0.3 μm.
  • Eyes with prior refractive surgery showed a statistically significant increase in induced HOAs (P = .02).
  • No other significant differences found in subgroup analyses.

Conclusions:

  • LAL treatments appear safe regarding HOA induction.
  • Prior refractive surgery is a potential risk factor for increased HOAs post-LAL treatment.
  • Further investigation into managing HOAs in this subgroup is warranted.