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Exercise Stress Test

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

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Related Experiment Video

Updated: Jan 11, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

Resistance Exercise Therapy After COVID-19 Infection: A Randomized Clinical Trial.

Colin Berry^1,2, Gemma McKinley³, Hannah K Bayes⁴

¹British Heart Foundation Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom.

JAMA Network Open

|November 10, 2025

Summary

Resistance exercise improved long COVID symptoms. A 3-month program enhanced walking distance, quality of life, and reduced anxiety and depression in adults post-COVID-19 infection.

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Last Updated: Jan 11, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

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Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

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Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Area of Science:

Rehabilitation Medicine
Infectious Disease Management
Exercise Physiology

Background:

Long COVID, a persistent condition post-COVID-19 infection, presents significant unmet therapeutic needs.
Exercise capacity and health status are often compromised in individuals experiencing Long COVID.

Purpose of the Study:

To evaluate the impact of a resistance exercise intervention on exercise capacity, health status, and safety in adults following COVID-19 infection.
To assess improvements in walking distance, quality of life, and mental health outcomes.

Main Methods:

A 2-arm, multicenter randomized clinical trial involving 233 adults diagnosed with COVID-19 within the prior 12 months.
The intervention group (117 participants) received a 3-month personalized resistance exercise program, while the control group (116 participants) received usual care.
Outcomes included the Incremental Shuttle Walk Test, European Quality of Life 5-Dimension 5-Level Instrument (EQ-5D-5L), Patient Health Questionnaire, and grip strength, assessed at baseline and 3 months.

Main Results:

The resistance exercise group showed a significantly greater improvement in Incremental Shuttle Walk Test distance compared to the control group (adjusted mean difference: 36.5 m; P=.02).
Significant improvements were also observed in the intervention group for health-related quality of life utility score (P=.02), anxiety and depression symptoms (P=.01), and handgrip strength (P=.002).
Adherence to the exercise intervention averaged 71%, equivalent to exercising 5 days per week.

Conclusions:

A 3-month resistance exercise program appears to be a safe and effective intervention for improving physical function and health status in adults with Long COVID.
This pragmatic intervention offers a potentially generalizable therapeutic strategy for managing persistent physical symptoms after COVID-19 infection.