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Development of Teleoperated Robotic System for Remote Intraocular Microsurgery.

Andi Xu1, Zhangkai Lian1, Wenben Chen1

  • 1Zhongshan Ophthalmic Center, Sun Yat-sen University, WHO Collaborating Centre for Eye Care and Vision, State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510623, China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|November 11, 2025
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Summary
This summary is machine-generated.

A new robotic telesurgery system offers micrometer-scale precision for remote microsurgery, significantly improving success rates and reducing complications in intraocular procedures. This technology aims to enhance surgical outcomes and expand access to specialized care globally.

Keywords:
intraocular surgeryremote microsurgerysurgical robottelemedicine

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Area of Science:

  • Ophthalmology
  • Robotics
  • Surgical Technology

Background:

  • Microsurgery offers precision but faces challenges in operational difficulty and surgeon availability.
  • Robotic telesurgery aims to overcome healthcare disparities but is limited by system precision, image quality, and latency.
  • Intraocular microsurgery presents unique challenges due to confined spaces and delicate tissues.

Purpose of the Study:

  • To introduce a novel teleoperated robotic system for enhanced remote microsurgery.
  • To evaluate the safety, feasibility, and efficacy of the robotic system in intraocular procedures.
  • To demonstrate the system's potential in improving surgical outcomes and accessibility.

Main Methods:

  • Development of a teleoperated robotic system with micrometer-scale precision and remote center of motion.
  • A randomized multicenter study involving in vivo subretinal injections in 51 rabbits.
  • Inclusion of ex vivo procedures for foreign body removal in porcine eyes and validation of communication stability in remote surgeries.

Main Results:

  • The teleoperated system achieved nearly twice the first-attempt success rate compared to manual surgery.
  • Significantly fewer surgical complications were observed with the robotic system.
  • Successful demonstration of versatility in foreign body removal and remote surgical procedures across distances.

Conclusions:

  • The developed teleoperated robotic system is safe, reliable, and versatile for remote intraocular procedures.
  • This technology has the potential to significantly improve surgical outcomes in microsurgery.
  • Remote microsurgery can broaden access to specialized ophthalmic care, addressing healthcare disparities.