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Follow-up Recommendations for Young, Average Risk Women With BI-RADS 3 Masses.

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No cancers were found in young women under 35 with BI-RADS 3 breast masses. A single 6-month ultrasound follow-up may suffice for these probably benign findings.

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Area of Science:

  • Radiology
  • Oncology
  • Breast Imaging

Background:

  • BI-RADS 3 assessments indicate probably benign findings on ultrasound.
  • Young women (<35 years) with BI-RADS 3 masses require clear follow-up guidelines.

Purpose of the Study:

  • To evaluate the malignancy rate and outcomes of BI-RADS 3 breast masses in women under 35.
  • To determine optimal follow-up intervals for these lesions.

Main Methods:

  • Retrospective cohort study of female patients <35 years with BI-RADS 3 masses on ultrasound.
  • Inclusion criteria: average risk, 6-month follow-up ultrasound, and ≥18 months imaging or biopsy.
  • Data collected: lesion characteristics, follow-up assessments, and pathology results.

Main Results:

  • 191 patients (228 lesions) met inclusion criteria; mean age 26.4 years.
  • Most lesions were stable (56%) or resolved (8%).
  • No malignancies were detected among 71 biopsied lesions; all were fibroadenomas.

Conclusions:

  • BI-RADS 3 masses in women <35 years have a 0% malignancy rate.
  • A single 6-month ultrasound follow-up may be adequate, followed by clinical surveillance.