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Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
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Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
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Prehabilitation for patients undergoing endoscopic submucosal dissection: a randomized controlled trial.

Biyun Jiang1, Shengdi Lu2, Yiling Yan3

  • 1Department of Nursing, Shanghai Sixth People's Hospital, Shanghai, China.

BMC Gastroenterology
|November 11, 2025
PubMed
Summary

Prehabilitation significantly enhances recovery after endoscopic submucosal dissection (ESD). A 4-week program improved functional capacity and psychological well-being, demonstrating a safe and effective strategy for better patient outcomes.

Keywords:
Endoscopic submucosal dissectionFunctional recoveryPrehabilitationQuality of lifeRandomized controlled trial

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Area of Science:

  • Gastroenterology
  • Surgical Recovery
  • Preventive Medicine

Background:

  • Endoscopic submucosal dissection (ESD) is a key therapy for early gastrointestinal neoplasms.
  • Patients undergoing ESD often experience reduced functional capacity and delayed recovery.
  • Prehabilitation has proven beneficial in major surgeries by improving physical fitness and recovery.

Purpose of the Study:

  • To investigate if a structured prehabilitation regimen before ESD enhances postoperative functional recovery and patient outcomes.
  • To compare the effects of a multimodal prehabilitation program versus standard care.

Main Methods:

  • A single-center, assessor-blinded randomized controlled trial involving 100 adults undergoing elective ESD.
  • Participants were randomized to a 4-week prehabilitation program (aerobic/resistance training, nutrition, psychological support) or usual care.
  • Primary outcome was the change in six-minute walk distance (6MWD) from baseline to 1 month post-procedure.

Main Results:

  • While 6MWD initially decreased in both groups, the prehabilitation group showed superior functional recovery by 3 months, surpassing baseline walking distance.
  • Prehabilitation led to significant improvements in handgrip strength, anxiety, and depression scores by 1 month.
  • Patients in the prehabilitation group reported greater gains in mental quality-of-life by 3 months, with no increase in complications or hospital stay.

Conclusions:

  • A 4-week multimodal prehabilitation program is a safe and effective strategy for patients undergoing ESD.
  • Prehabilitation significantly improves postoperative functional capacity and psychological well-being.
  • This approach enhances patient-centered outcomes following ESD procedures.