Related Experiment Video

Updated: Jan 11, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
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Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

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Impact of Environmental Pollutant Exposures on Bronchopulmonary Dysplasia

Joseph M Collaco1, Nicole Stephenson2, Brianna C Aoyama1

  • 1Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA.

Pediatric Pulmonology
|November 12, 2025
PubMed

Insights

Environmental pollutants impact respiratory outcomes in premature infants with bronchopulmonary dysplasia (BPD). Addressing modifiable risk factors like pollution exposure may improve long-term lung health for this vulnerable population.

Area of Science:

  • Pediatric Pulmonology
  • Environmental Health
  • Neonatology

Background:

  • Bronchopulmonary dysplasia (BPD) is a common chronic respiratory disorder in children.
  • Long-term respiratory outcomes in premature infants with BPD vary significantly.
  • Early life environmental exposures are linked to lifelong respiratory consequences.

Purpose of the Study:

  • To review the effects of environmental pollutants on respiratory outcomes in premature infants.
  • To specifically examine the impact of pollutants on infants with BPD.
  • To identify targets for improving long-term health in this population.

Main Methods:

  • Literature review of existing studies.
  • Analysis of data on environmental exposures and respiratory outcomes.
  • Focus on premature infants, particularly those with BPD.

Main Results:

  • Environmental exposures significantly influence respiratory health in premature infants.
  • Specific data exists for the impact of pollutants on infants with BPD.
  • Early exposures can lead to reduced lung function later in life.

Conclusions:

  • Environmental pollutants pose a risk to respiratory health in premature infants with BPD.
  • Modifiable risk factors, such as pollution exposure, are key targets for intervention.
  • Interventions aimed at reducing environmental exposures may improve long-term outcomes for vulnerable infants.

Keywords:
air pollutionbronchopulmonary dysplasiachronic lung diseasedisparitieselectronic cigaretteenvironmentoutpatientsmoke

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