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Published on: June 14, 2024
Cardiomyopathy Associated with Subclinical Becker Muscular Dystrophy in a Patient Presenting with Anesthesia-induced
Kento Kumai1, Hiroki Mochizuki1, Takuya Watanabe1
1Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Japan.
None:
Becker muscular dystrophy (BMD)-associated cardiomyopathy may be overlooked in patients with dilated cardiomyopathy (DCM). We herein report a case of cardiomyopathy related to BMD in which anesthesia-induced rhabdomyolysis led to a diagnosis of BMD. The patient experienced anesthesia-induced rhabdomyolysis during cardiac resynchronization therapy. The patient became inotrope-dependent, and a left ventricular assist device was safely implanted by considering the use of anesthetic agents to avoid rhabdomyolysis. The abnormal immunohistochemical staining pattern of dystrophin protein in the myocardium and dystrophin gene mutation confirmed the diagnosis of BMD. BMD should thus be considered in patients with DCM to prevent perioperative complications including rhabdomyolysis.
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