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Related Experiment Video

Updated: Jan 11, 2026

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Exploring medication adherence in Behçet's disease following COVID-19: a mixed-methods study.

Emily Arden-Close1, Fay Sweeting2, Danielle Guy2

  • 1Bournemouth University, School of Psychology, Poole, BH12 5BB, UK. eardenclose@bournemouth.ac.uk.

Orphanet Journal of Rare Diseases
|November 13, 2025
PubMed
Summary
This summary is machine-generated.

Medication adherence in Behçet's Disease is generally good, influenced by beliefs in necessity and concerns about medicines. Patients balance concerns with perceived benefits, highlighting the need for condition-specific advice.

Keywords:
Behçet's diseaseCOVID-19Concerns regarding medicinesMedication adherenceMixed methodsNecessity of medicines

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Area of Science:

  • Rheumatology
  • Autoimmune Diseases
  • Pharmacology

Background:

  • Behçet's Disease is a rare autoimmune disorder requiring long-term medication.
  • Understanding medication adherence is crucial for managing chronic conditions like Behçet's Disease.

Purpose of the Study:

  • To identify predictors of medication adherence in Behçet's Disease.
  • To explore the decision-making process influencing medication adherence in patients with Behçet's Disease.

Main Methods:

  • A mixed-methods study combining quantitative (n=89) and qualitative (n=16) approaches.
  • Quantitative analysis involved questionnaires on demographics, adherence, beliefs, perceptions, trust, and COVID-19 fear.
  • Qualitative analysis utilized semi-structured interviews and thematic analysis.

Main Results:

  • Belief in medicine necessity and concerns explained 16% of adherence variance.
  • Key themes included illness experience, medication routines, facilitators (doctor recommendation, symptom relief), barriers (side effects, perceived ineffectiveness), and COVID-19 related issues.
  • Patients demonstrated good understanding of their disease and trust in physicians.

Conclusions:

  • Medication adherence in Behçet's Disease is generally good, with patients balancing concerns against perceived necessity.
  • Addressing patient concerns about medicines, side effects, and perceived efficacy is vital.
  • Providing updated, condition-specific advice can improve adherence and patient outcomes.