Related Experiment Video
Updated: Jul 10, 2026
09:47
Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
Published on: February 19, 2016
10.0K
Pectin-Coated Zeolitic Imidazolate Framework-8 Nanoparticles: A Dual-Responsive System for Controlled Carbendazim
Yan Chen1,2, Ragab Abouzeid1, Qinglin Wu1
1School of Renewable Natural Resources, Louisiana State University Agricultural Center, Baton Rouge, LA 70803, USA.
Materials (Basel, Switzerland)
|November 13, 2025
Summary
This study developed a novel dual-responsive nanofungicide (MBC@ZTA-PT) using eco-friendly materials for sustainable agriculture. The controlled-release system enhances fungicide efficiency and reduces environmental impact.
Area of Science:
- Agricultural Science
- Materials Science
- Nanotechnology
Background:
- Chemical fungicides face challenges in efficiency and sustainability.
- Controlled-release nanomaterials offer improved delivery and reduced application frequency.
- Developing eco-friendly alternatives is crucial for sustainable agriculture.
Purpose of the Study:
- To synthesize a dual-responsive nanofungicide (MBC@ZTA-PT) for enhanced carbendazim (MBC) delivery.
- To investigate the role of tannic acid (TA) etching and pectin (PT) from sweet potato peels.
- To evaluate the controlled-release properties and responsiveness to pH and enzymes.
Main Methods:
- Synthesized MBC@ZTA-PT by loading carbendazim into ZIF-8, followed by tannic acid etching and pectin addition.
- Utilized pectin extracted from sweet potato peels as a biodegradable additive.
- Assessed cumulative release rates at different pH values (5 and 7) and in the presence of pectinase over 96 hours.
Main Results:
- Tannic acid etching significantly improved MBC loading efficiency.
- The MBC@ZTA-PT system demonstrated dual-responsive release triggered by pH and pectinase.
- Cumulative release rates reached 33.12% at pH 7, 59.00% at pH 7 with pectinase, and 70.74% at pH 5 with pectinase after 96 hours.
Conclusions:
- The synthesized MBC@ZTA-PT exhibits excellent controlled-release properties and responsiveness.
- This eco-friendly nanofungicide enhances MBC utilization efficiency and minimizes environmental hazards.
- MBC@ZTA-PT presents a promising strategy for sustainable plant disease management.
Related Concept Videos
01:22Modified-Release Drug Delivery Systems: Rate-Programmed I
Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
01:30Modified-Release Drug Delivery Systems: Stimuli-Activated
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...
01:24Modified-Release Drug Delivery Systems: Site-Targeted
Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
01:24Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...