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Do Updated Calcitonin Thresholds More Accurately Predict Lymph Node Metastasis in Medullary Thyroid Cancer?-Reply

Yuxin Du1,2, Yu Wang1,2

  • 1Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.

JAMA Otolaryngology-- Head & Neck Surgery
|November 13, 2025
PubMed
Abstract

No abstract available in PubMed .

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
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