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Updated: Jan 11, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
[Kaposi's disease]
1Service de dermatologie, hôpital Cochin, AP-HP Centre, université Paris Cité, 123, boulevard de Port-Royal, 75014 Paris, France.
None:
Kaposi's disease is a primarily dermatological disorder characterized histologically by a proliferation of endothelial cells of lymphatic origin, linked to the HHV-8 virus, and occurring most often in a context of reduced immunity, whether linked to age, HIV infection or immunosuppressive therapy. There are 5 epidemiological forms of Kaposi's disease, all of which are predominantly male and of advanced age, especially in the classic form. In the majority of cases, the disease is indolent, but in certain situations, it can become aggressive, either locally or through involvement of internal organs such as the lung and digestive tract. Whenever possible, treatment focuses on restoring immunity. Unfortunately, in some patients this is impossible and/or ineffective, and chemotherapy or, more recently, immunotherapy, is required.
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