Using Thue Morse structure and magnified defect resonance as cancer sensor

Area of Science:

• Photonics
• Biomedical Sensing
• Optical Detection

Background:

• Quasi-periodic photonic crystals offer unique optical properties.
• Oral cancer detection requires sensitive and precise diagnostic tools.
• Parity-time (PT) symmetry provides a framework for manipulating light propagation.

Purpose of the Study:

• To develop a novel quasi-periodic photonic crystal sensor for sensitive oral cancer detection.
• To utilize parity-time symmetry conditions to enhance sensor performance.
• To analyze the optical transmittance spectra of the proposed sensor structure.

Main Methods:

• Proposed a photonic crystal structure based on the Thue-Morse sequence using SiO2 and Si.
• Employed the transfer matrix method with MATLAB simulation to analyze transmittance spectra.
• Utilized parity-time symmetry optimization in the Terahertz band to amplify resonant modes.

Main Results:

• The optimized sensor demonstrated extremely high sensitivity (9.0 × 10^9 %/RIU) for cancer cell detection.
• Achieved a remarkable resonance peak magnification with transmittance up to 3.16 × 10^9%.
• The gain/loss factor was identified as critical for amplifying resonance mode transmittance within the photonic band gap.

Conclusions:

• The proposed quasi-periodic photonic crystal structure with PT symmetry enables sensitive distinction of pathological tissues.
• The sensor's resonant spectral response is key to its high sensitivity for oral cancer detection.
• This technology holds significant potential for precise optical detection of oral cancer.