Related Experiment Video
Updated: May 5, 2026

A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity
Published on: July 12, 2018
Emerging Risk of Campylobacter spp. Infection Associated With Anti-BCMA and Anti-GPRC5D Bispecific Antibodies
Idoia Bilbao1, María Ansón1, Sara Villar2
1Infectious Diseases Division, Clínica Universidad de Navarra, Pamplona, Spain.
None:
Bispecific antibodies directed against BCMA and GPRC5D have shown remarkable efficacy in patients with refractory multiple myeloma; however, concerns regarding infection risk are emerging. In a cohort of 85 treated patients, we observed a notable incidence of Campylobacter infections, including 5 bloodstream and 5 gastrointestinal episodes, affecting 9 individuals. This unexpectedly high burden of infection highlights the vulnerability of this immunocompromised population and underscores the urgent need for studies evaluating targeted preventive and surveillance strategies.
More Related Videos
06:08Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
Published on: February 10, 2023
06:37Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety
Published on: September 15, 2023
Related Concept Videos
Bacterial Gastroenteritis
Clinical Significance of Antibiotic Resistance