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Published on: May 16, 2025
Economic Burden of Rheumatoid Arthritis in Iran: A Societal Perspective
Mehdi Rezaee1,2, Farhad Lotfi3, Ahmad Gholami4,5
1Department of Management, Economics and Health Policy, School of Health Bushehr University of Medical Sciences Bushehr Iran.
The economic burden of rheumatoid arthritis (RA) in Iran was $6388.64 per patient-year in 2022. Direct medical costs, particularly medications, were the primary driver of this significant financial impact on patients and society.
Area of Science:
- Health Economics
- Rheumatology
- Public Health
Background:
- Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease with substantial economic implications.
- Uncontrolled RA significantly burdens patients and healthcare systems.
- Understanding the economic burden is crucial for effective management and resource allocation.
Purpose of the Study:
- To quantify the total economic burden of rheumatoid arthritis (RA) in Iran.
- To identify the key cost drivers associated with RA management in the Iranian context.
- To provide data-driven recommendations for mitigating the economic impact of RA.
Main Methods:
- A cross-sectional study was conducted in 2022, involving 765 RA patients.
- Prevalence-based and bottom-up approaches were utilized for cost estimation.
- The human capital approach was employed to calculate indirect costs.
Main Results:
- The overall economic burden of RA in Iran was estimated at $6388.64 per patient-year in 2022.
- Mean annual RA costs varied by disease state: $6268.24 (remission), $6248.00 (low), and $6729.43 (moderate-to-severe).
- Direct medical costs, especially medication expenses, constituted the most significant component.
Conclusions:
- Rheumatoid arthritis imposes a considerable economic burden on Iranian patients and society.
- Reducing the economic burden necessitates strategies like domestic production of RA medications and enhanced home care services.
- Policy interventions should focus on optimizing medication accessibility and care delivery models.
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