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Confirming Rupture of Membranes with Intra-Amniotic Fluorescein Dye Test
Katherine Freedy1, Sarah K Dotters-Katz2, Bobby May2
1Duke University School of Medicine, Durham, North Carolina, United States.
AJP Reports
|November 14, 2025
Summary
Sodium fluorescein dye successfully confirmed preterm prelabor rupture of membranes (PPROM) in two patients when indigo carmine was unavailable. Visual documentation of positive fluorescein dye tests under UV light aids PPROM diagnosis.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Diagnostic Imaging
Background:
- Preterm prelabor rupture of membranes (PPROM) diagnosis can be challenging with inconclusive initial evaluations.
- Traditional diagnostic methods may face limitations, such as reagent shortages, necessitating alternative approaches.
