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Updated: Jan 11, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Exercising through cancer: Physical activity as medicine for cancer care
David M Nash1, Lauren V Terry2, Mark A Febbraio2
1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Melbourne, VIC, Australia; Salk Institute for Biological Studies, La Jolla, CA, USA.
Abstract:
Exercise holds significant potential as an adjunct therapy in cancer, extending beyond quality-of-life improvements to influencing tumor progression, treatment response, and survival. Its clinical integration remains limited by variability in models, heterogenous interventions, and the absence of predictive biomarkers. As the field progresses, identifying molecular effectors of exercise, in addition to emphasizing practical clinical translation, is essential. This commentary highlights the anti-tumor effects of exercise and evaluates how exercise can advance from supportive care to a targeted, evidence-based component of cancer treatment.
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