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Exercise as a therapeutic intervention for long-lasting and chronic diseases
Mark A Febbraio1, Bente Klarlund Pedersen2
1Baker Heart & Diabetes Institute, Melbourne, VIC, Australia; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
Regular physical activity, or "exercise as medicine," can prevent and treat chronic lifestyle diseases. This approach combats the rise in non-contagious diseases despite increased life expectancy.
Area of Science:
- Exercise physiology
- Preventive medicine
- Chronic disease management
Background:
- Global life expectancy has risen significantly in the last century.
- Physical activity levels have decreased dramatically over the past 100 years.
- Non-contagious diseases (NCDs) like cardiovascular disease, type 2 diabetes, cognitive diseases, and cancer are increasing.
Purpose of the Study:
- To discuss the concept of "exercise as medicine" for NCD treatment.
- To provide evidence for the mechanisms of physical activity in preventing and managing NCDs.
Main Methods:
- Review of scientific literature on exercise and NCDs.
- Analysis of direct biological mechanisms linking physical activity to disease prevention and progression.
Main Results:
- Physical activity can prevent the onset of NCDs.
- Regular exercise can slow the progression of existing NCDs.
- Evidence supports specific physiological pathways through which exercise impacts NCDs.
Conclusions:
- Exercise is a viable and effective therapeutic strategy for NCDs.
- Understanding the mechanisms of "exercise as medicine" is crucial for public health.
- Promoting physical activity is essential for combating the epidemic of chronic lifestyle diseases.
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