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Updated: Jan 11, 2026

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Nanotechnology and Nanoparticles: Implications in Dentistry.

Anu Priya Guruswamy Pandian1, Abhishek Walhekar2, Sudha Rani Jujuru3

  • 1Private Practice, Los Angeles, CA 91367, USA.

Dental Clinics of North America
|November 14, 2025
PubMed
Summary
This summary is machine-generated.

Nanodentistry uses nanoparticles (NPs) to improve dental treatments with enhanced antimicrobial and regenerative properties. Further research on biocompatibility is needed for widespread clinical adoption of these advanced dental materials.

Keywords:
AntibacterialNanocarriersNanocompositesNanodentistryNanoparticlesNanorobotsNanotechnologySilver nanoparticles

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Area of Science:

  • Biomaterials Science
  • Nanotechnology in Medicine
  • Dental Research

Background:

  • Nanodentistry leverages nanoparticles (NPs) and nanomaterials to revolutionize dental care.
  • Modifying materials at the nanoscale significantly enhances their properties for dental applications.

Purpose of the Study:

  • To review key scientifically researched NPs in dentistry.
  • To discuss the potential and challenges of nanodentistry.
  • To highlight the need for further biocompatibility investigations.

Main Methods:

  • Literature review of scientifically researched NPs in dentistry.
  • Analysis of NPs' improved physicochemical and biologic properties.
  • Evaluation of NPs' utility across various dental specialities.

Main Results:

  • NPs offer superior antimicrobial, regenerative, and diagnostic capabilities in dentistry.
  • Demonstrated broad utility in preventive, restorative, periodontics, prosthodontics, orthodontics, and oral cancer therapy.
  • Identified biocompatibility concerns requiring further investigation.

Conclusions:

  • Nanodentistry presents significant advancements for dental treatment modalities.
  • Further research, particularly on biocompatibility, is crucial for clinical translation.
  • NPs hold promise for enhanced dental care but require rigorous validation.