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Related Experiment Video

Updated: Jan 11, 2026

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A bibliometric advances in posterior capsule opacification.

Wei Si1, Yuxuan Wang2, Su Xu2

  • 1Department of Ophthalmology, Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.

Medicine
|November 15, 2025
PubMed
Summary

Posterior capsule opacification (PCO) research shows a shift from early cataract surgery materials to recent focus on cellular migration and surface modification. Bibliometric analysis reveals key trends and emerging hotspots in PCO studies.

Keywords:
CiteSpacePCOVOS viewerbibliometricscluster analysisvisualization

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Area of Science:

  • Ophthalmology
  • Biomedical Research
  • Bibliometrics

Background:

  • Posterior capsule opacification (PCO) is a frequent complication after cataract surgery, impacting vision.
  • PCO incidence varies widely (5-50%) within the first year post-surgery.
  • Understanding PCO research trends is crucial for clinical advancement.

Purpose of the Study:

  • To conduct a bibliometric analysis of PCO research.
  • To explore the evolution of research frontiers and emerging hotspots in PCO.
  • To identify key publications, institutions, and research themes.

Main Methods:

  • Bibliometric analysis of 1951 PCO articles (2000-2023) from Web of Science.
  • Utilized CiteSpace and VOSviewer for data analysis.
  • Examined publication output, country, institution, author, journal, keyword, and citation data.

Main Results:

  • The United States led in publications; University of Vienna was the most productive institution.
  • Liliana Werner was the most prolific author; Journal of Cataract & Refractive Surgery published the most articles.
  • Research focus evolved from "polymethylmethacrylate" and "extracapsular cataract" to "migration," "surface modification," and "mesenchymal transition."

Conclusions:

  • Bibliometric analysis provides insights into PCO research trends.
  • Identifies key themes and emerging areas for future investigation.
  • Facilitates informed clinical research directions and collaborations.