Constructing cationic hydroxyl-functionalized hypercrosslinked polymer for effectively enriching and detecting...

Developing sensitive and accurate methods for detecting endocrine-disrupting chemicals (EDCs) is highly significant. Herein, a hydroxy-functionalized cationic hypercrosslinked polymer (OH-iHCP) was synthesized for the first time. The OH-iHCP has good adsorption properties for phenolic EDCs. The adsorption mechanism of EDCs on OH-iHCP mainly includes π-π* stacking, hydrogen bond and electrostatic interaction. A highly viable analytical method for determination of trace EDCs in green shrimp, Basa fish and milk was established by employing OH-iHCP as solid phase extraction adsorbent combined with liquid chromatography-mass spectrometry. The detection limit of the method was 1.45-4.50 ng g^-1, 3.00-7.00 ng g^-1 and 0.04-0.15 ng mL^-1 for green shrimp, Basa fish and milk, respectively. The recoveries of the method were 80.7 %-118 %, with the relative standard deviation less than 8.0 %. This study demonstrates that the developed OH-iHCP could be served as a valuable adsorbent for adsorption and separation of phenolic organic pollutants.