Related Experiment Video
Updated: Jan 11, 2026

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
Published on: September 27, 2019
Pruritis Ani
Michael Newman1, Dipen Maun2, Scott Dolejs2
1Ascension St. Vincent Surgical Residency Program, Ascension St. Vincent Ortho Center, 2001 West 86th Street, Indianapolis, IN 46260, USA.
Pruritus ani, or anal itching, is a common condition often caused by identifiable factors. Addressing the root cause and implementing proper hygiene significantly improves symptoms.
Area of Science:
- Gastroenterology
- Dermatology
Background:
- Pruritus ani is defined as severe itching of the perianal skin.
- Symptoms can be intermittent, constant, acute, or chronic.
Purpose of the Study:
- To outline the etiologies, diagnostic workup, and therapeutic modalities for pruritus ani.
- To emphasize the importance of identifying and correcting underlying causes.
Main Methods:
- Review of current medical literature on pruritus ani.
- Discussion of diagnostic approaches including patient history and physical examination.
- Overview of treatment strategies.
Main Results:
- An underlying cause is identified in 75% of pruritus ani cases.
- Correction of underlying causes often leads to significant symptom improvement.
- Treatment involves addressing the cause, hygiene education, trigger avoidance, and symptom management.
Conclusions:
- Effective management of pruritus ani relies on identifying and treating the underlying etiology.
- Patient education on anorectal hygiene and trigger avoidance is crucial.
- A comprehensive approach combining medical and behavioral interventions ensures optimal outcomes.
Related Concept Videos
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Accessory Structures of the Skin: Hair and Hair Follicles
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Psychosexual Stages of Personality: Anal
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Anatomy of the Genitourinary System II: Bladder and Urethra
Urethra
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male...

